Alcohol-Associated Liver Disease

Alcohol-associated liver disease disease occurs when excessive alcohol consumption causes liver damage.

your quick guide to this page

what is alcohol-associated liver disease?

Alcohol-associated liver disease occurs when an individual consumes alcohol excessively and usually over a long period of time. Excessive alcohol consumption can lead to 3 main types of liver disease:

  • Alcohol- associated fatty liver disease where alcohol causes extra fat cells to build in the liver.
  • Alcohol-associated hepatitis where alcohol consumption leads to inflammation of liver cells.
  • Alcohol-associated cirrhosis where damage leads to irreversible liver scarring greatly impacting the liver’s ability to perform vital functions.

Majority of liver damage from alcohol consumption occurs when patients consume alcohol regularly over a long period of time, but can also be caused by individuals drinking large amounts within a short period of time.

fast facts

  • Alcohol-associated liver disease can occur in individuals who are not dependent on alcohol.
  • Approximately 90% of individuals who excessively consume alcohol on a regular basis  have fatty liver disease.
  • Alcohol-associated liver diseases are most common in individuals between the ages of 40 and 50 but can be seen at any age.

symptoms

Majority of individuals with alcohol-associated liver disease will not feel symptoms until they are in later stages. When individuals do experience symptoms, common ones for alcohol-associated liver disease include:

  • Weight loss
  • Fatigue
  • Jaundice (yellowing of eyes and skin)
  • Nausea and vomiting
  • Brain fog or confusion
  • Blood in stools

lifestyle impacts

Since most people with alcohol-associated liver disease do not experience symptoms at early stages, patients are likely to live a normal life. If the disease progresses into later stages and permeant damage like cirrhosis with continued drinking, individuals may experience liver failure which can cause more serious lifestyle impacts like seizures, severe mental confusion, and even death.

what can I do?

prevention

The most important way to prevent alcohol-associated liver diseases is to limit alcohol consumption as it is toxic to liver cells. Canada’s Low Risk Drinking Guidelines is an excellent resource to help individuals make informed decisions about their alcohol consumption. It is recommended that:

  • Women consume less than 2 standard drinks each day, 10 standard drinks per week, or 3 standard drinks on special occasions
  • Men consume less than 3 alcoholic beverages each day, 15 standard drinks per week, or 4 standard drinks on special occasions
  • Pregnant individuals avoid consuming alcohol.

In Canada a standard drink equals:

  • a bottle of beer (12 oz., 341 ml, 5% alcohol)
  • a glass of wine (5 oz., 142 ml, 12% alcohol)
  • a shot glass of spirits (1.5 oz., 43 ml, 40% alcohol)
  • a bottle of cider (12 oz., 341 ml, 5% alcohol)

Following these guidelines are likely to reduce your risk of developing alcohol-associated liver disease although all consumption of alcohol can lead to health complications.

diagnosis

The first step to diagnosing alcohol-associated liver disease is a comprehensive medical exam discussing medical history and lifestyle habits. Common diagnostic tests to determine if an individual has alcohol-associated liver disease include:

  • Blood tests to measure liver enzyme levels
  • Imaging tests such as an ultrasound, X-ray, or CT scan
  • Liver biopsy to confirm diagnosis

treatment

In early stages, the most important form of treatment is to stop the consumption of alcohol. If patients do not have severe irreversible liver scarring, the liver has the ability to regenerate and restore its functioning when alcohol is no longer consumed. Individuals in later stages may require a liver transplant based on the liver’s ability to perform its vital functions.

additional resources

Here are a few questions to ask your doctor or medical team:

  • What is the status of my liver?
  • What type of alcohol-associated liver disease do I have?
  • What lifestyle changes should I make to prevent further liver damage?
  • Will I need a liver transplant?