Hepatitis D

Hepatitis D is a viral infection which causes inflammation of liver cells.

your quick guide to this page

what is hepatitis d?

Hepatitis D (HDV) is a rare but serious liver infection that only occurs in people who already have hepatitis B. It can cause more severe liver damage, but with the right care, it can be prevented and managed. You can only get hepatitis D if you already have hepatitis B, as the hepatitis D virus needs hepatitis B to survive and grow in your body. You can be infected with both viruses at the same time (co-infection), or get hepatitis D later if you already have hepatitis B (superinfection). There are two types of hepatitis D:

  • Acute hepatitis D: This is a short-term infection that can be treated by the patient’s immune system alone.
  • Chronic hepatitis D: This is a long-term infection that occurs when the immune system is unable to fight the viral infection.

Having both hepatitis B and D can lead to faster and more severe liver damage, increasing the risk of cirrhosis, liver failure, and liver cancer, as the disease often progresses more quickly than hepatitis B alone.

How does hepatitis D spread?

Hepatitis D spreads the same way as hepatitis B, through blood or bodily fluids. This includes:

  • Sharing needles or drug equipment
  • Unprotected intimate connections
  • Unsterile medical, piercing, or tattoo equipment
  • From mother to baby during childbirth

If you have hepatitis B, talk to your doctor about whether you should be tested for hepatitis D, especially if you were born in or have lived in regions where hepatitis D is more common, such as Africa, Asia, Eastern Europe, the Middle East, or South America. Also, if you have risk factors like injection drug use, blood transfusions in certain countries, or unsafe tattooing or piercing.

fast facts

  • Approximately 5% of people with hepatitis B also have hepatitis D.
  • 1 in 6 cases of cirrhosis (liver scarring) may be caused by hepatitis D.
  • Hepatitis D is most common in Africa, Asia, Europe, and South America and rarely in North America.

symptoms

Symptoms for hepatitis D are similar to other viral hepatitis infections. Symptoms usually occur within 2 months of exposure. Common symptoms for hepatitis D include:

  • Dark urine and light stools
  • Nausea and vomiting
  • Fever
  • Fatigue
  • Jaundice (yellowing of the skin and eyes)
  • Joint pain

lifestyle impacts

Hepatitis D is a severe infection that can lead to life altering complications such as cirrhosis,  liver failure, and potentially death. These severe complications can require patients to receive a liver transplant. Patients with this disease are required to make healthy lifestyle changes to support immune system functioning to help reduce inflammation. These include:

  • Eating a balanced diet
  • Participating in regular exercise
  • Limiting alcohol consumption
  • Avoiding smoking

what can I do?

prevention

The main prevention method for hepatitis D is to receive the hepatitis B vaccination. Additional ways to prevent contracting hepatitis D include:

  • Sterilizing needles used for tattoos and piercings
  • Practicing safe sex
  • Stop consumption of drugs
  • Avoid sharing personal hygiene items such as toothbrushes and razors.

There’s no vaccine specifically for hepatitis D, but the hepatitis B vaccine protects against both viruses. Getting vaccinated against hepatitis B is the most effective way to prevent hepatitis D.

diagnosis

The initial step to diagnosing an individual with hepatitis D is to test the patient for hepatitis B. A blood test can be used to determine if the patient has hepatitis B. If the test is positive for hepatitis B, a second blood test can be done to determine if the individual has hepatitis D.

treatment

New options for the treatment of hepatitis D are currently being studied and may become available in the future. Regular monitoring by a liver specialist is key to managing the disease and protecting your liver health.

additional resources

Here are a few questions to ask your doctor or medical team:

  • What is the status of my liver?
  • What lifestyle modifications should I make to support my liver health?
  • What treatment options are available for hepatitis D?
  • Are there any clinical trials I can participate in for hepatitis D?

Liver Canada Resources