What is sarcoidosis?

Sarcoidosis is a multi-system disease of unknown cause in which nests of cells appear in many tissues, including the lung, lymph nodes and liver.  The disease is recognized in many parts of the world, but is more prevalent in western societies.  The overall prevalence appears to be in the order of 20 in 100,000.

What are the symptoms and physical complications of sarcoidosis?

Liver biopsy reveals distinct lesions which develop due to an inflammatory reaction, which are referred to as hepatic granulomas.  These lesions are present in about 75 per cent of patients.

Pulmonary lymph node involvement is typical.  Fibrosis or scarring of the lungs may be widespread and lung function may be abnormal.

In addition to liver and lung involvement, there may be other symptoms associated with the disease such as the enlargement of lymph nodes, facial nerve paralysis, arthritis, cystic bone lesions, excess calcium deposited in the kidneys, heart disease and neurological problems which may include peripheral nerve damage and diabetes.

How is sarcoidosis treated?

There is no specific treatment for sarcoidosis.  However, symptoms are treated as needed.

If you would like more information on sarcoidosis or any other liver disease, please contact us.

The CLF offers Living with Liver Disease programs. You can also help others living with liver disease by volunteering or donating in support of the CLF's research and education programs.
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